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Torsten O Nielsen Selected Research

Synovial Sarcoma (Synovioma)

1/2022Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102.
1/2021Synovial Sarcoma Oncogenesis Revealed by Single-Cell Profiling.
12/2018The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.
1/2018The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.
12/2017Death by HDAC Inhibition in Synovial Sarcoma Cells.
1/2017HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma.
6/2016Identification of cytotoxic agents disrupting synovial sarcoma oncoprotein interactions by proximity ligation assay.
4/2015NY-ESO-1 (CTAG1B) expression in mesenchymal tumors.
2/2015Synovial sarcoma: recent discoveries as a roadmap to new avenues for therapy.
2/2014Activating transcription factor 2 in mesenchymal tumors.
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Torsten O Nielsen Research Topics

Disease

106Neoplasms (Cancer)
10/2022 - 12/2002
81Breast Neoplasms (Breast Cancer)
10/2022 - 01/2004
22Sarcoma (Soft Tissue Sarcoma)
12/2020 - 10/2003
21Synovial Sarcoma (Synovioma)
01/2022 - 10/2003
10Carcinoma (Carcinomatosis)
02/2022 - 12/2002
6Carcinogenesis
01/2019 - 01/2005
5Myxoid Liposarcoma
01/2019 - 09/2009
5Ewing Sarcoma (Sarcoma, Ewing)
10/2012 - 10/2003
4Triple Negative Breast Neoplasms
01/2022 - 01/2020
4Neoplasm Metastasis (Metastasis)
10/2015 - 09/2009
4Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
07/2009 - 07/2004
3Giant Cell Tumors (Giant Cell Tumor)
01/2020 - 05/2008
3Chondrosarcoma
04/2015 - 06/2007
3Endometrial Stromal Sarcoma
05/2013 - 01/2005
3Neurofibroma
10/2012 - 08/2004
3Leiomyosarcoma
10/2012 - 10/2003
3Giant Cell Tumor of Tendon Sheath
04/2010 - 06/2007
3Aggressive Fibromatosis (Desmoid)
06/2007 - 01/2005
3Solitary Fibrous Tumors
06/2005 - 10/2003
2Liposarcoma
01/2021 - 12/2020
2Genetic Translocation (Chromosomal Translocation)
11/2011 - 09/2007
2Neurofibrosarcoma (MPNST)
01/2010 - 08/2004
2Clear Cell Sarcoma
06/2008 - 01/2005
2Osteosarcoma (Osteogenic Sarcoma)
06/2007 - 07/2006
2Dermatofibrosarcoma
06/2007 - 08/2004
2Fibroma (Fibromatosis)
06/2005 - 01/2005
1Hypoxia (Hypoxemia)
03/2021

Drug/Important Bio-Agent (IBA)

41Biomarkers (Surrogate Marker)IBA
02/2022 - 04/2006
30Estrogen ReceptorsIBA
10/2022 - 08/2004
25Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2004
22Phenobarbital (Luminal)FDA Link
01/2022 - 08/2004
13Oncogene Proteins (Oncogene Protein)IBA
01/2021 - 08/2005
13Progesterone Receptors (Progesterone Receptor)IBA
01/2020 - 08/2007
11Biological ProductsIBA
10/2022 - 06/2007
11ParaffinIBA
12/2021 - 12/2003
11Formaldehyde (Formol)FDA Link
12/2021 - 12/2003
10ErbB Receptors (EGF Receptor)IBA
02/2022 - 10/2003
10Hormones (Hormone)IBA
02/2022 - 10/2008
10AntibodiesIBA
01/2020 - 12/2002
9TamoxifenFDA LinkGeneric
12/2021 - 05/2009
7Immune Checkpoint InhibitorsIBA
12/2020 - 11/2015
7Histone Deacetylase InhibitorsIBA
12/2017 - 06/2008
6Transcription Factors (Transcription Factor)IBA
02/2022 - 09/2007
6AnthracyclinesIBA
12/2021 - 03/2009
6Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2020 - 03/2009
6Fluorouracil (Carac)FDA LinkGeneric
01/2020 - 03/2009
6Histone Deacetylases (Histone Deacetylase)IBA
03/2019 - 06/2007
6human ERBB2 proteinIBA
10/2018 - 12/2008
5NestinIBA
12/2021 - 11/2013
5DNA (Deoxyribonucleic Acid)IBA
09/2021 - 12/2003
5Methotrexate (Mexate)FDA LinkGeneric
01/2020 - 02/2012
5taxaneIBA
01/2020 - 03/2009
5Pharmaceutical PreparationsIBA
01/2019 - 08/2005
5Indicators and Reagents (Reagents)IBA
01/2018 - 07/2006
5Epidermal Growth Factor (EGF)IBA
10/2015 - 06/2006
5Monoclonal AntibodiesIBA
01/2010 - 12/2006
4Keratins (Keratin)IBA
02/2022 - 08/2004
4Coloring Agents (Dyes)IBA
02/2022 - 07/2006
4Phosphotransferases (Kinase)IBA
01/2017 - 10/2004
4Keratin-5 (Keratin 5)IBA
10/2008 - 08/2004
4Complementary DNA (cDNA)IBA
05/2008 - 07/2004
3MA 12 (MA12)IBA
12/2021 - 08/2012
3Estrogens (Estrogen)FDA Link
12/2021 - 01/2017
3Epirubicin (Ellence)FDA LinkGeneric
01/2020 - 02/2012
3Macrophage Colony-Stimulating FactorIBA
01/2020 - 01/2010
3Docetaxel (Taxotere)FDA Link
01/2019 - 03/2009
3RNA (Ribonucleic Acid)IBA
12/2017 - 06/2007
3tyrosine receptor (receptor, tyrosine)IBA
01/2017 - 08/2005
3Insulin-Like PeptidesIBA
09/2009 - 11/2008
3tanespimycin (17AAG)IBA
01/2009 - 01/2004
3Imatinib Mesylate (Gleevec)FDA Link
06/2007 - 10/2004
3Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
06/2007 - 08/2005
2Complement System Proteins (Complement)IBA
12/2020 - 02/2008
2UbiquitinIBA
03/2019 - 01/2018
2GemcitabineFDA Link
01/2019 - 06/2014
2Dihydrotachysterol (AT 10)IBA
01/2018 - 07/2007
2Levamisole (Decaris)FDA Link
01/2018 - 02/2017
2quisinostatIBA
12/2017 - 01/2017
2Trastuzumab (Herceptin)FDA Link
11/2017 - 08/2005
2Messenger RNA (mRNA)IBA
01/2017 - 10/2012
2Crystallins (Crystallin)IBA
10/2015 - 01/2006
2Co-Repressor ProteinsIBA
02/2014 - 12/2009
2RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
04/2012 - 12/2009
2LigandsIBA
07/2009 - 06/2007
2Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2009 - 08/2005
2romidepsin (FK228)FDA Link
06/2008 - 06/2008
2beta CateninIBA
06/2007 - 01/2005
2Gefitinib (Iressa)FDA Link
01/2007 - 08/2005
1malate dehydrogenase (decarboxylating)IBA
01/2022
1AntioxidantsIBA
01/2022
1Inositol (Myoinositol)IBA
12/2021
1ProgesteroneFDA LinkGeneric
12/2021
1DNA-Activated Protein KinaseIBA
09/2021
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
09/2021
1Carbonic Anhydrase IXIBA
03/2021

Therapy/Procedure

38Therapeutics
11/2021 - 08/2005
17Drug Therapy (Chemotherapy)
12/2021 - 06/2007
9Immunotherapy
11/2021 - 04/2015
6Adjuvant Chemotherapy
02/2021 - 03/2009
2Radiotherapy
02/2021 - 06/2015